Adenovirus (ADV) is icosahedral non-enveloped virus with double-stranded DNA (dsDNA) genomes, belonging to the family Adenoviridae. Adenovirus have become one of the most promising gene delivery tools due to several advantages, including high transduction efficiency, broad tropism for different tissue targets, and large cargo capacities for transient targeted gene delivery.

| Adenoviral Vector Construction

We offer different adenovirus types and ADV packaging systems and provide you with customized ADV construction services.

Human Ad5 adenovirus:AdEasy system, AdMAX system, and we have developed the BigAdeno® system: Self-developed, BigAdeno® has reduced immunogenicity and a significantly larger capacity, which can accommodate ~10 kb of space for cargo gene(s).

Chimeric Ad5/F35 adenovirus：AdEasy system, the chimeric design of Ad5/F35 adenovirus has been highly instrumental in expanding the tropism of adenoviral vectors to cell lines such as hematopoietic cells, primitive stem cells, vascular smooth muscle cells and CAR-negative tumor cells.